Reduced costs, increased process efficiency, and added flexibility through multi-column technology…all designed with disposable components to be practical and functional within virtually all bioprocessing environments. Tarpon's BioSMB systems deliver technology-anchored efficiency, practicality and continuity regardless of scale:

BioSMB Efficiency:

• Fit new high titer processes into existing facilities
• Reduce all supporting buffer tanks and service demands in a facility
• Process more product in less space
• Reduce chromatographic media use by 80% in clinical manufacturing

BioSMB Economics:

• Significantly reduce total capital costs of biopharmaceutical production
• Decrease COGs in all operation modes
• Reduce purification costs by 40-50%, resulting in a savings of 30% of total costs at all production levels
• Prepacked and tested columns decrease operating costs by eliminating need for packing operation and storage space, increasing facility uptime, and enabling rapid change over between products

BioSMB Practicality:

• Patented disposable technology enables economic and efficient biopharmaceutical purification
• Technology provides an open platform that can be used with any separation modality and conserves current process chemistries
• Multi-column approach enables fully disposable process including the capture step
• Fully disposable downstream allows dedicated flow paths for multi-product facilities
• Sizing is driven by volume of upstream bioreactors;
• Higher titers can be accommodated by adding disposable columns and changing process parameters
• No storage or under utilization of chromatographic media (especially Protein A in clinical settings)
• Suitable for CGMP manufacturing (production systems)